Extremely Low Birth Weight and Accelerated Biological Aging

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Minerals and extremely low birth weight infants

The 80% of bone mineralisation occurs in the third trimester of pregnancy. The daily fetal requirement is 310 mg of calcium and 170 mg of phosphorus [1]. The bone mineral density (BMD) correlates positively with gestational age, weight and length [2]. At birth, extremely premature infants (ELBWI)canpresent hypocalcaemia because of interruption of the maternal calcium supply, high level of calci...

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Hypothyroxinemia in extremely low birth weight infants

Hypothyroxinemia of prematurity (HOP) is a transient alteration in thyroid hormone availabilityfound in more than half of extremely low birth weight infants (ELBW) born at less than 30 weeks [1]. HOP is characterized by very low total T4 (TT4) and free T4 (FT4) levels with a normal or low thyroid stimulating hormone (TSH); TT4 and FT4 show a nadir at 7-10 days of life and they may remained low ...

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Targeted short-term fluconazole prophylaxis among very low birth weight and extremely low birth weight infants.

OBJECTIVES To assess whether targeted short-term fluconazole prophylaxis reduces late-onset (>3 days of age) invasive fungal infection (IFI) among very low birth weight infants and extremely low birth weight (ELBW) infants and to assess mortality rates, toxicity, and costs associated with this intervention. METHODS An observational study of 2 subsequent epochs of inborn infants with birth wei...

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Preterm Birth of Extremely Low Birth Weight Infants

Approximately 13% of births in the United States are preterm, defined as occurring before 37 weeks of gestation. This results in more than 540,000 infants a year born prematurely. In other words, one out of every 8 infants is born premature. Even more disturbing is that despite advances in neonatal and perinatal medicine, the incidence of prematurity has increased by 36% since the 1980’s. Over ...

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Does Extremely Low Birth Weight Predispose to Low-Renin Hypertension?

Low birth weight and prematurity are risk factors for hypertension in adulthood. Few studies in preterm or full-term born children reported on plasma renin activity (PRA). We tested the hypothesis that renin might modulate the incidence of hypertension associated with prematurity. We enrolled 93 prematurely born children with birth weight <1000 g and 87 healthy controls born at term, who were a...

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ژورنال

عنوان ژورنال: Pediatrics

سال: 2021

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.2020-001230